Prevalence of depressive symptoms and their impact on quality of life in patients with drug-resistant focal epilepsy (IMDYVA study)

Abstract

Compared to other studies, the rate of depressive symptoms was high (60% in DRE and 30% in CFE patients). MADRS and BDI-II showed a positive correlation. Prior to the study, depressive symptoms were underdiagnosed in a large proportion of patients. Clinical diagnosis of depressive symptoms and not seizure frequency was associated with poorer mean QOLIE-31 scores.