Pharmacologic Antagonism of the Oral Aversive Taste-Directed Response to Capsaicin in a Mouse Brief Access Taste Aversion Assay

The capsaicin receptor: a heat-activated ion channel in the pain pathway

Michael J. Caterina, Mark Schumacher, Makoto Tominaga et al. · Nature · 1997 · 9.1K citations

Life Sciences, Neurobiology, Pharmacology +16

Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor

Michael J. Caterina, Andreas Leffler, Annika B. Malmberg et al. · Science · 2000 · 3.5K citations

Life Sciences, Neurobiology, Neuroscience +17

The Receptors for Mammalian Sweet and Umami Taste

Grace Q. Zhao, Yifeng Zhang, Mark A. Hoon et al. · Cell · 2003 · 1.3K citations · Full text

Life Sciences, Biochemistry, Neuroscience +14

TRPA1 Contributes to Cold, Mechanical, and Chemical Nociception but Is Not Essential for Hair-Cell Transduction

Kelvin Y. Kwan, Andrew Allchorne, Melissa A. Vollrath et al. · Neuron · 2006 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

AMG 9810 [(E)-3-(4-t-Butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a Novel Vanilloid Receptor 1 (TRPV1) Antagonist with Antihyperalgesic Properties

Narender R. Gavva, Rami Tamir, Yusheng Qu et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 388 citations

Medicine, Medicinal Chemistry, Pharmacology +15