Charge‐Shifting Click Capsules with Dual‐Responsive Cargo Release Mechanisms

Abstract

The assembly of responsive layer-by-layer-assembled click polymer capsules that exhibit dual-responsive cargo release mechanisms for the controlled release of cargo is reported. The capsules show reversible size changes between pH 6 and 7.4. The synergistic effects of pH and redox-potential allow for rapid and efficient cargo release at simulated intracellular conditions.