Concepedia

THE SYNTHESIS OF 2-AZA-ADENOSINE-3′,5′-CYCLIC PHOSPHATE VIA 1,<i>N</i>6-ETHENO-ADENOSINE-3′,5′-CYCLIC PHOSPHATE

Nobuyuki Yamaji, Motohiko Kato

Chemistry Letters · 1975 · 17 citations · 2 references

DOI

Concepts

Abstract

Abstract Treatment of 2-aza-1,N6-etheno-c-AMP with NBS or Br2 under mild conditions gave 2-aza-c-AMP in a high yield. Therefore, the route c-AMP→2-aza-1,N6-etheno-c-AMP→2-aza-c-AMP offers an excellent way to synthesize the last compound.

References

2

Proton magnetic resonance study of the conformations of 3',5'-cyclic nucleotides

Barry J. Blackburn, Roy D. Lapper, Ian C. P. Smith · Journal of the American Chemical Society · 1973 · 100 citations

, , +12

Analogs of adenosine 3′,5′-cyclic phosphate. II. Synthesis and enzymatic activity of derivatives of 1,N6-ethenoadenosine 3′,5′-cyclic phosphate

Gordon H. Jones, Devangachinta Murthy, Derek Tegg et al. · Biochemical and Biophysical Research Communications · 1973 · 31 citations

, , +12