Variability of Skin Autofluorescence Measurement Over 6 and 12 Weeks and the Influence of Benfotiamine Treatment

Abstract

In patients with T2DM, repeated, timely spaced SAF measurements have an intra-subject variability of below 11%. Using these data, sample sizes were calculated for interventional studies aiming at reducing SAF. Benfotiamine treatment for 6 weeks did not significantly influence SAF; for this, a longer-term therapy is probably needed.