Relation between HFE Mutations and Mild Iron-Overload Expression

A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis

John N. Feder, Andreas Gnirke, Zenta Tsuchihashi et al. · Nature Genetics · 1996 · 3.7K citations

Life Sciences, Genetics, Molecular Genetics +12

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

John N. Feder, David M. Penny, Alivelu Irrinki et al. · Proceedings of the National Academy of Sciences · 1998 · 838 citations

Life Sciences, Genetics, Molecular Biology +15

Prevalence of Hemochromatosis among 11,065 Presumably Healthy Blood Donors

Corwin Q. Edwards, Linda M. Griffen, David E. Goldgar et al. · New England Journal of Medicine · 1988 · 638 citations

Medicine, Genetics, Hematology +17

The Hemochromatosis Founder Mutation in HLA-H Disrupts β2-Microglobulin Interaction and Cell Surface Expression

John N. Feder, Zenta Tsuchihashi, Alivelu Irrinki et al. · Journal of Biological Chemistry · 1997 · 479 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

Mutation Analysis in Hereditary Hemochromatosis

Ernest Beutler, Terri Gelbart, Carol West et al. · Blood Cells Molecules and Diseases · 1996 · 427 citations

Life Sciences, Genetics, Molecular Genetics +14