Circulation · 1973 · 395 citations · 0 references
MedicineCardiologyPathologyAutopsy PathologyDiagnostic ImagingNecropsy PathologyCardiovascular DiseaseCardiovascular PathologyCoronary AngiographyCoronary Artery DiseaseIschemic Heart DiseaseVascular PathologyCardiovascular Autopsy TechniqueCoronary Artery Disease DetectionCoronary Artery Disease ImagingCoronary HemodynamicsCoronary Lesion AssessmentCoronary Vascular ImagingCoronary Vessel Wall Imaging
Correlative studies were carried out on the coronary arteriograms made during diagnostic procedures and on the specimens obtained at necropsy in 10 cases of coronary heart disease. Of the 134 segments of coronary arteries available for both studies, 44 (33%) were given false-negative arteriographic diagnosis of obstructive atherosclerosis. Factors which may underlie this discrepancy include (1) radiographic technic, (2) projection used, (3) a slitlike lumen adjacent to the atheroma, (4) comparison of severely obstructed segments involved but less severely obstructed, and (5) misinterpretation from the specimen of obstruction present in life.