Leukemia & lymphoma/Leukemia and lymphoma · 2015 · 40 citations · 16 references
MedicinePediatricsRadiologyDiagnostic ImagingDiagnostic RadiologyPediatric RadiologyChest RadiologyPediatric ImagingPediatric LeukemiasPediatric Nuclear ImagingPulmonary ImagingPulmonary Nodule EvaluationChest Radiography FindingsChest Radiography In ChildrenCohen's Kappa InterpretationKappa CoefficientKappa StatisticMcnemar's TestPediatric Leukemia ImagingPulmonary Nodule Diagnosis
Immunocompromised children with hematological malignancies are at increased risk of developing potentially fatal pulmonary infections. Early detection and prompt treatment is critical to combat morbidity and mortality in these children. Twenty-six children with leukemia (age range: 5-13years) presenting with fever and neutropenia were included in this prospective study, which was approved by the institutional ethics committee. All patients underwent HRCT and MRI of the chest on the same day. The findings of HRCT and MRI were compared, with HRCT as the standard of reference. There was perfect agreement between MRI and CT examinations findings by kappa test (κ = 1). No significant difference was observed between the two modalities by the McNemar test (p > 0.05). Rapid lung MRI is technically feasible; has a high correlation, sensitivity and specificity to CT scan; and can emerge as the first line modality for the detection of pulmonary nodules in children with leukemia and persistent febrile neutropenia.
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Radiation Risk to Children From Computed Tomography
Alan S. Brody, Donald P. Frush, Walter Huda et al. · PEDIATRICS · 2007 · 608 citations
Medicine, Pediatrics, Radiology +17
Focal Ground-Glass Opacity Detected by Low-Dose Helical CT
Masao Nakata, Hideyuki Saeki, Ichiro Takata et al. · CHEST Journal · 2002 · 276 citations