Isotope effect profiles in the N-demethylation of N,N-dimethylanilines: a key to determine the pK_aof nonheme Fe(<scp>iii</scp>)–OH complexes

Abstract

N-demethylation of N,N-dimethylanilines promoted by [(N4Py)Fe(IV)=O](2+) occurs by an electron transfer-proton transfer (ET-PT) mechanism with a rate determining PT step. From the bell-shaped curve of the KDIE profile it has been estimated that the pK(a) of [(N4Py)Fe(III)-OH](2+) is 9.7.