Publication | Closed Access
EFFECT OF HYPOGLYCEMIA AND ANOXIA ON THE SURVIVAL PERIOD OF INFANT AND ADULT RATS AND CATS
11
Citations
0
References
1943
Year
FitnessBrain DevelopmentMammalian PhysiologyEducationInfant BrainOxidative StressPhysiological ResearchAnimal PhysiologyOxygen DeprivationHypoxia (Medicine)AnesthesiologyRespiration (Physiology)Fetal NeurodevelopmentRelative CapacityNeurophysiologyPhysiologyDiabetesPediatricsTissue OxygenationMetabolismMedicineComparative Physiology
THE literature contains a number of reports on the comparative effects of anoxia in infants and adults of the same species as well as between members of different species (Kabat, 1940; Fazekas, Alexander and Himwich, 1941; Himwich, Bernstein, Herrlich, Chesler and Fazekas, 1942). In general, it was found that newborn of all species examined possess greater resistance to anoxia than adults, a resistance dependent upon the greater capacity of the infant brain to withstand oxygen deprivation. Glucose (Himwich and Nahum, 1932), like oxygen, is an obligate of cerebral metabolism. We, therefore, extended this report beyond the study of anoxia to include the relative capacity of infants and adults in resisting hypoglycemia. In addition, the duration of survival of adult animals when exposed to the combined effects of anoxia with either hypoglycemia or hyperglycemia were observed.