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CD24 V/V is an allele associated with the risk of developing multiple sclerosis in the Spanish population
43
Citations
10
References
2006
Year
Allele CNeurological DisorderGeneticsImmunologyGenetic EpidemiologyPathologyCd24 V/vHuman PolymorphismImmune-related Gene PolymorphismClinical GeneticsCd24 GenePublic HealthMolecular DiagnosticsNeuroimmunologyAutoimmune DiseaseSpanish PopulationAutoimmunityGenetic FactorEpidemiologyAllelic VariantMultiple SclerosisMedicine
The allele C in the CD24 gene has been related to multiple sclerosis (MS). In this work we check this single nucleotide polymorphism (SNP) in a population of 135 patients and 285 controls. Our results confirm the association between the V/V genotype at aa 57 of this gene and MS and highlight the importance of taking into account the origin of the subjects to avoid a population bias.
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