Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 1976 · 316 citations · 2 references
Life SciencesCell BiologyDevelopmental BiologyCell DivisionDevelopmental Cell BiologyEmbryologyApoptosis In DevelopmentNeural Circuit FormationNeural DevelopmentNeuronal DevelopmentApoptosis In Invertebrate DevelopmentApoptosis In Neural DevelopmentC. Elegans Developmental ModelsNematode Developmental BiologyNeural Developmental Cell DeathNeuronal MorphogenesisVentral Nerve Cord
56 nerve cells are added to the ventral cord and associated ganglia of Caenorhabditis elegans at about the time of the first larval moult. These cells are produced by the uniform division of 13 neuroblasts followed by a defined pattern of cell deaths. Comparison with the data in the previous paper suggests that there is a relationship between the ancestry of a cell and its function. The significance of programmed cell death is discussed.
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THE DNA OF <i>CAENORHABDITIS ELEGANS</i>
John Sulston, Sydney Brenner · Genetics · 1974 · 597 citations · Full text