Identification of immunodominant alloreactive T-cell epitopes on the Jka red blood cell protein inducing either Th1 or Th2 cytokine expression

Abstract

Although antibodies implicated in red blood cell (RBC) alloimmunization have been studied for many years, little is known about helper T-cell responses that drive their production.[1][1]-[3][2] The aim of this work was to determine T-cell antigenic determinants involved in T-cell responses against