The Effect on Intracuff Pressure of Various Nitrous Oxide Concentrations Used for Inflating an Endotracheal Tube Cuff

Abstract

Nitrous oxide (N(2)O) diffuses into the cuff, equilibrating at a smaller concentration than the gas mixture with which patients are ventilated. Our data indicate that inflation of the cuff with 40% N(2)O is recommended to prevent both excessive endotracheal cuff pressure and air leaks during anesthesia with 67% N(2)O, reducing postoperative sore throats.