Effects of a novel glucagon receptor antagonist (Bay 27-9955) on glucagon-stimulated glucose production in humans

Mechanism by which metformin reduces glucose production in type 2 diabetes.

Ripudaman S. Hundal, Sylvie Dufour, Didier Laurent et al. · Diabetes · 2000 · 1.1K citations · Full text

Life Sciences, Endocrinology, Physiology +17

Studies of pancreatic alpha cell function in normal and diabetic subjects

Roger H. Unger, E Aguilar-Parada, Walter A. Müller et al. · Journal of Clinical Investigation · 1970 · 837 citations · Full text

Medicine, Endocrinology, Internal Medicine +10

Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study.

I Magnusson, Douglas L. Rothman, Lee D. Katz et al. · Journal of Clinical Investigation · 1992 · 761 citations · Full text

Life Sciences, Endocrinology, Physiology +15

Fasting hyperglycemia in non-insulin-dependent diabetes mellitus: Contributions of excessive hepatic glucose production and impaired tissue glucose uptake

Ralph A. DeFronzo, Eleuterio Ferrannini, Donald C. Simonson · Metabolism · 1989 · 515 citations

Medicine, Endocrinology, Internal Medicine +16

Relationships between insulin secretion, insulin action, and fasting plasma glucose concentration in nondiabetic and noninsulin-dependent diabetic subjects.

Clifton Bogardus, Stephen Lillioja, Barbara V. Howard et al. · Journal of Clinical Investigation · 1984 · 405 citations · Full text

Medicine, Endocrinology, Diabetology +10