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Prevention of Muscle Necrosis in an Experimental Neurovascular Island Muscle Flap by a Vasodilator Drug—Isoxsuprine
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1979
Year
Vasodilator Drug—isoxsuprineMuscle FunctionEngineeringPharmacotherapySurgeryOrthopaedic SurgeryNeuromuscular BlockadeFlap PhysiologySoft Tissue InjuryMuscle InjurySkeletal MuscleBiomechanicsVascular SurgeryApplied PhysiologyMuscle NecrosisAnesthetic PharmacologyMechanobiologyVascular PharmacologyPharmacologyClinical FlapSoft Tissue ReconstructionMedicinePlastic SurgeryAnesthesiology
We report an experiment that demonstrates one means to prevent necrosis in an experimental island muscle flap. The results imply that necrosis of skeletal muscle in a clinical flap could be prevented by treatment with isoxsuprine.