Publication | Open Access
Microwave-assisted synthesis of nitrogen-containing heterocycles
118
Citations
99
References
2013
Year
Medicinal ChemistryChemical EngineeringEngineeringHeterocyclicNatural SciencesGreen ChemistryMw Heating ApproachOrganic ChemistryChemistryMw-assisted ReactionHeterocycle ChemistrySynthesis MethodMicrowave-assisted SynthesisMicrowave SynthesisSynthetic ChemistryMw-assisted Synthesis
Abstract In the recent years, microwave (MW) radiation is widely used as a source of heating in organic synthesis. Since the discovery of the MW heating approach, MW-assisted reaction has emerged as a new green-method in organic synthesis as it provides spectacular accelerations, higher yields under milder reaction conditions, and higher product purities, and it reduces pollution of the environment through the use of solvent-free reaction protocols. N-containing heterocycles hold a special place among pharmaceutically significant natural products and synthetic compounds needed for any developed human society. Therefore, organic chemists have been engaged in extensive efforts to produce these compounds following various greener techniques, primarily to circumvent growing environmental concerns. In this review, we discuss only the MW-assisted synthesis of N-containing heterocyclic compounds.
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