Oxidative stress and inflammation in the normal airways and blood of patients with lung cancer and COPD

8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions.

Keith C. Cheng, D S Cahill, Hiroshi Kasai et al. · Journal of Biological Chemistry · 1992 · 1.8K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Systemic Oxidative Stress in Asthma, COPD, and Smokers

Irfan Rahman, Deborah Morrison, Kenneth Donaldson et al. · American Journal of Respiratory and Critical Care Medicine · 1996 · 780 citations

Life Sciences, Immunology, Allergy +16

Spirometric reference values from a Mediterranean population.

Josep Roca, J. Sanchís, A Agustí-Vidal et al. · PubMed · 1986 · 502 citations

Health Professions, Physiology, Exercise Testing +16

4-Hydroxy-2-Nonenal, a Specific Lipid Peroxidation Product, Is Elevated in Lungs of Patients with Chronic Obstructive Pulmonary Disease

Irfan Rahman, Annemarie A. M. van Schadewijk, Ann J. L. Crowther et al. · American Journal of Respiratory and Critical Care Medicine · 2002 · 456 citations

Life Sciences, Biochemistry, Apoptosis +16

Assessing the Relationship Between Lung Cancer Risk and Emphysema Detected on Low-Dose CT of the Chest

Juan P. de‐Torres, Gorka Bastarrika, Juan P. Wisnivesky et al. · CHEST Journal · 2007 · 456 citations · Full text

Medicine, Oncology, Radiology +16