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C58 and AKR mice of all ages develop motor neuron disease after lactate dehydrogenase-elevating virus infection but only if antiviral immune responses are blocked by chemical or genetic means or as a result of old age

Neurodegenerative DiseasesMotor Neuron DiseaseNeurovirologyMedicinePathogenesisImmunologyAkr MiceDegenerative PathologyDegenerative DiseaseNeurologyNeurodegenerationNeuropathologyNeuroimmunologyViral ImmunityGenetic MeansNeuroinflammation