Expression of Kir 4.1 in human astrocytic tumors: Correlation with pathologic grade

Mediation of Neuronal Apoptosis by Enhancement of Outward Potassium Current

Shan Ping Yu, Chen-Hsiung Yeh, Stefano L. Sensi et al. · Science · 1997 · 575 citations

Medicine, Neuroscience, Pharmacology +17

A Primary Role for K+ and Na+ Efflux in the Activation of Apoptosis

Carl D. Bortner, Francis M. Hughes, John A. Cidlowski · Journal of Biological Chemistry · 1997 · 561 citations · Full text

Life Sciences, Biophysics, Cell Biology +16

Genetic Inactivation of an Inwardly Rectifying Potassium Channel (Kir4.1 Subunit) in Mice: Phenotypic Impact in Retina

Paulo Kofuji, Paul W. Ceelen, Kathleen R. Zahs et al. · Journal of Neuroscience · 2000 · 456 citations · Full text

Medicine, Cell Biology, Ophthalmology +17

Na ⁺ /H ⁺ exchanger‐dependent intracellular alkalinization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation‐associated phenotypes

Stephan J. Reshkin, Antonia Bellizzi, Sandra Caldeira et al. · The FASEB Journal · 2000 · 369 citations

Medicine, Cell Biology, Oncology +17

An inwardly rectifying K⁺ channel, Kir4.1, expressed in astrocytes surrounds synapses and blood vessels in brain

K. Higashi, Akikazu Fujita, Atsushi Inanobe et al. · American Journal of Physiology-Cell Physiology · 2001 · 306 citations

Medicine, Neurobiology, Neuroscience +16