Oppositely Charged Gelatin Nanospheres as Building Blocks for Injectable and Biodegradable Gels

Abstract

Injectable and biodegradable gels have been formed by a bottom-up synthesis strategy employing oppositely charged gelatin nanospheres as particulate building blocks. These gels are formed by electrostatic interactions between and tight packing of gelatin nanospheres of opposite charge. Due to their favorable clinical handling, ease of functionalization, and cost-effectiveness, these gels show great potential as injectable gels for tissue regeneration.