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Publication | Open Access

Expression and Function of Recombinant S1179D Endothelial Nitric Oxide Synthase in Canine Cerebral Arteries

DOIFull Paper Access

19

Citations

24

References

2002

Year

Masahiko Akiyama, Daihiko Eguchi, Deborah A. Weiler, Timothy O’Brien, Imre Kovesdi, Ramona S. Scotland, William C. Sessa, Zvonimir S. Katušić
Stroke

Abstract

Our results suggest that in cerebral arteries, expression of recombinant S1179DeNOS increases basal production of NO and inhibits the vasoconstrictor effect of endothelin-1. This effect may have therapeutic application in prevention and treatment of cerebrovascular diseases.

References

YearCitations

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