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A Convenient Synthesis off Coumarins by Denitro-cyclization
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1986
Year
Combinatorial ChemistryMaloric AcidBioorganic ChemistryNatural SciencesOrganic ChemistryConvenient SynthesisCoumarins ConsistsChemistryHeterocycle ChemistryPharmacologyDerivative (Chemistry)Synthetic ChemistryNew MethodNatural Product Synthesis
A new method for the synthesis of coumarins consists of the condensation of 2-nitrobenzaldehydes with maloric acid and denitro-cyclization of the resultant o-nitrobenzylidenemalonic acids using copper in quinoline.