Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism - Concepedia

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Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism

DOI Full Paper Access

56

Citations

33

References

2014

Year

Chaowei Hu, Jiewen Zhu, X E Guo, Wen‐Pin Chen, X-L Qiu, Bryan Ngo, Rao-Chi Chien, Yao Wang, Chang‐Youh Tsai, Guang Wu,

Novel Small MoleculesCell SignalingDeath-trap MechanismMedicineReceptor Tyrosine KinaseCell DeathNek2 DegradationCell BiologyTumor SuppressorCancer BiologyRadiation OncologyCancer ResearchTumor BiologyCancer Growth

References

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