Concepedia

Publication | Closed Access

Biologically active human islet amyloid polypeptide/amylin in transgenic mice

DOI

11

Citations

0

References

1997

Year

Karen L. van Hulst, Walter Born, Roman Muff, Cor Oosterwijk, Marinus A. Blankenstein, Cornelis JM Lips, Jan A. Fischer, Jo W.M. Höppener
European Journal of Endocrinology

Abstract

This study has shown that correctly processed hIAPP produced in transgenic mouse pancreatic beta cells exhibits full biological activity. The results validate these transgenic mice for the study of (patho)physiological roles of hIAPP in vivo.