Concepedia

Dicationic dithiocarbamate carbapenems with anti-MRSA activity

Hideaki Imamura, Norikazu Ohtake, Hideki Jona, Aya Shimizu, Minoru Moriya, Hiroki Sato, Yuichi Sugimoto, Chinatsu Ikeura, Hideo Kiyonaga, Masato Nakano,

Bioorganic & Medicinal Chemistry · 2001 · 68 citations · 17 references

DOI

Concepts

References

17

Synthetic Carbapenem Antibiotics. I. 1-b-Methylcarbapenem

L. D. Cama, David H. Shih, Florence Baker et al. · Heterocycles · 1984 · 198 citations · Full text

, , +14

Synthesis of an Anti-Methicillin-Resistant <i>Staphylococcus aureus </i>(MRSA) Carbapenem via Stannatrane-Mediated Stille Coupling

Mark S. Jensen, Chunhua Yang, Yi Hsiao et al. · Organic Letters · 2000 · 85 citations

, , +6

Dicationic 2-fluorenonylcarbapenems: Potent anti-MRS agents with improved solubility and pharmacokinetic properties

Mark L. Greenlee, Joanne B. Laub, Gregory P. Rouen et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 61 citations · Full text

, , +17

Therapeutic efficacy of BO-3482, a novel dithiocarbamate carbapenem, in mice infected with methicillin-resistant Staphylococcus aureus

R Nagano, Kenji Shibata, Toshio Naito et al. · Antimicrobial Agents and Chemotherapy · 1997 · 43 citations · Full text

, , +17

Preparation of crystallinep-nitrobenzyl 2-hydroxymethyl carbapenem as a key intermediate for the anti-MRS carbapenem L-786,392

Nobuyoshi Yasuda, Chunhua Yang, Kenneth M. Wells et al. · Tetrahedron Letters · 1999 · 37 citations

, , +9