A Scalable, Efficient Gold‐Catalyzed Oxidative Phosphonation of <i>sp</i>³ CH Bonds using Air as Sustainable Oxidant

Abstract

Abstract A scalable, efficient gold‐catalyzed oxidative phosphonation of sp 3 CH bonds with various diarylphosphine oxides and dialkyl phosphites has been developed by using air as a sustainable oxidant under mild reaction conditions. It provides an easy access to α‐amino phosphonic compounds in high yields with a broad reaction scope. The safe, convenient and environmentally benign process makes this protocol very promising.