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A Study of the Effects of Gonadotropin-Releasing Hormone on Human Mood and Behavior
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1978
Year
Human MoodGynecologyGonadotropin-releasing HormonePsychologySocial SciencesReproductive EndocrinologyHealthy Male VolunteersNeuroendocrine MechanismAutomatized Motor TasksGnrh AdministrationBehavioral SciencesStress HormonePsychiatryBehavioral NeuroscienceEndocrine MechanismDepressionEndocrinologyMood DisordersBiological PsychiatryNeuroscienceMedicinePsychopathologyReproductive HormoneGonadotropin Biology
Gonadotropin-releasing hormone in doses up to 500 microgram was administered to 12 healthy male volunteers. Luteinizing hormone and testosterone levels increased subsequent to GnRH administration. No immediate effects of GnRH on mood and behavior were noted, though an increase in alertness, a decrease in anxiety and fatigue, and an increased speed of performance on automatized motor tasks were noted several hours after GnRH administration.