Concepedia

Gallium (<scp>iii</scp>)-catalysed bromocyanation of alkynes: regio- and stereoselective synthesis of β-bromo-α,β-unsaturated nitriles

Masahito Murai, Ryo Hatano, Sachie Kitabata, Kouichi Ohe

Chemical Communications · 2010 · 82 citations · 39 references

DOI

Concepts

Abstract

Treatment of arylacetylenes and cyanogen bromide in ClCH(2)CH(2)Cl with a catalytic amount of GaCl(3) afforded (Z)-β-bromoacrylonitriles with high regio- and stereoselectivity.

References

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