Synthesis of β-Substituted-α-[(trimethylsilyl)oxy]acrylonitriles from α, β-Unsaturated Aldehydes

Abstract

Abstract The condensation of trimethylsilylcyanide with α, β-unsaturated aldehydes, followed by DBU catalyzed isomerization of the intermediate 0-silylated cyanohydrins, constitutes a facile synthesis of β-substituted- α-[(trimethylsilyl)oxy]acrylonitriles.