Metabolomic analysis of the toxic effect of chronic low-dose exposure to acephate on rats using ultra-performance liquid chromatography/mass spectrometry

Induction of Tumors in Mice by Genomic Hypomethylation

François Gaudet, John Hodgson, Amir Eden et al. · Science · 2003 · 1.5K citations

Medicine, Genetics, Oncology +16

Global metabolic profiling procedures for urine using UPLC–MS

Elizabeth J. Want, Ian D. Wilson, Helen Gika et al. · Nature Protocols · 2010 · 1.1K citations

Life Sciences, Biochemistry, Pharmaceutical Analysis +14

Pattern recognition methods and applications in biomedical magnetic resonance

John C. Lindon, Elaine Holmes, Jeremy K. Nicholson · Progress in Nuclear Magnetic Resonance Spectroscopy · 2001 · 422 citations

Engineering, Bioengineering, Biomedical Engineering +14

Chemometric Models for Toxicity Classification Based on NMR Spectra of Biofluids

Elaine Holmes, Andrew W. Nicholls, John C. Lindon et al. · Chemical Research in Toxicology · 2000 · 277 citations

Pharmacy, Pharmacology, Toxicology +15

Metabonomic Characterization of Genetic Variations in Toxicological and Metabolic Responses Using Probabilistic Neural Networks

Elaine Holmes, Jeremy K. Nicholson, G.E. Tranter · Chemical Research in Toxicology · 2001 · 177 citations

Life Sciences, Biochemistry, Toxicology +17