Ca2+ release from endoplasmic reticulum is mediated by a guanine nucleotide regulatory mechanism

Inositol trisphosphate, a novel second messenger in cellular signal transduction

Michael J. Berridge, Robin F. Irvine · Nature · 1984 · 6.1K citations

Signal Transduction, Biochemistry, Natural Sciences +9

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

H. Streb, R.F. Irvine, Michael J. Berridge et al. · Nature · 1983 · 2.6K citations

Molecular Physiology, Signal Transduction, Biochemistry +11

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

Martin Rodbell · Nature · 1980 · 1.8K citations

Signal Transduction, Biochemistry, Membrane Transduction +12

myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.

Suresh K. Joseph, Andrew P. Thomas, Rebecca J Williams et al. · Journal of Biological Chemistry · 1984 · 566 citations · Full text

Second Messenger, Hormonal Mobilization, Cellular Pharmacology +20

The second messenger linking receptor activation to internal Ca release in liver

Gillian M. Burgess, P P Godfrey, Jerry S. McKinney et al. · Nature · 1984 · 555 citations

Second Messenger, Signal Transduction, Hepatology +13