Rapid Communications in Mass Spectrometry · 1998 · 28 citations · 0 references
Natural SciencesChemistryMaterials ScienceAnalytical ChemistryPolymer ChemistryPolymer MaterialsChromatographyMass SpectrometryPolymer AnalysisPolymer CharacterizationPolymer StructureSupercritical Fluid ChromatographyMatrix-assisted Laser Desorption Ionization Time-of-flight Mass SpectrometryMatrix-assisted Laser Desorption/ionizationMatrix-assisted Laser Desorption/ionization Time-of-flight Mass SpectrometryPolymer Mass SpectrometryPolymer Matrix-assisted Laser Desorption/ionizationPolymethyl MethacrylateSupercritical Fluid Chromatography ColumnsSupercritical Fluid Chromatography-mass Spectrometry
The laser power dependence on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) has been studied by mixing equimolar amounts of three kinds of monodisperse poly(methyl methacrylate) (PMMA). Employing optimum laser power, the molecular weight information of the polydisperse PMMA was obtained, and the result compared with that obtained from supercritical fluid chromatography (SFC) and gel permeation chromatography (GPC). The average molecular weight of PMMA, obtained from the MALDI-MS experiment, was found to be higher than that obtained from both SFC and GPC. The result implies that MALDI-MS can detect higher molecular species of the polymer.Copyright © 1998 John Wiley & Sons, Ltd.