A first case of congenital TTP on the African continent due to a new homozygous mutation in the catalytic domain of ADAMTS13

Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura

Gallia G. Levy, William C. Nichols, Eric C.‐Y. Lian et al. · Nature · 2001 · 1.8K citations · Full text

Medicine, Genetics, Molecular Genetics +10

FRETS‐VWF73, a first fluorogenic substrate for ADAMTS13 assay

Koichi Kokame, Yuko Nobe, Yoshihiro Kokubo et al. · British Journal of Haematology · 2005 · 601 citations

Medicine, Biochemistry, Molecular Biology +17

Mutations and common polymorphisms in <i>ADAMTS13</i> gene responsible for von Willebrand factor-cleaving protease activity

Koichi Kokame, Masanori Matsumoto, Kenji Soejima et al. · Proceedings of the National Academy of Sciences · 2002 · 411 citations

Life Sciences, Genetics, Molecular Biology +17

Recovery and Half-Life of von Willebrand Factor-Cleaving Protease after Plasma Therapy in Patients with Thrombotic Thrombocytopenic Purpura

Rodolfo Robles, Beat Morselli, P Sandoz et al. · Thrombosis and Haemostasis · 1999 · 218 citations · Full text

Medicine, Hematology, Pathology +17

von Willebrand factor cleaving protease and ADAMTS13mutations in childhood TTP

Reinhard Schneppenheim, Ulrich Budde, Florian Oyen et al. · Blood · 2003 · 216 citations · Full text

Life Sciences, Genetics, Molecular Biology +9