Thiazole derivatives as inhibitors of cyclooxygenases in vitro and in vivo

Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full <i>in vitro</i> analysis

Timothy D. Warner, Francesco Giuliano, Ivana Vojnovic et al. · Proceedings of the National Academy of Sciences · 1999 · 1.5K citations · Full text

Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic.

Jaime L. Masferrer, Ben S. Zweifel, Pamela T. Manning et al. · Proceedings of the National Academy of Sciences · 1994 · 1.3K citations · Full text

Inflammation, Molecular Pharmacology, Selective Inhibition +14

Enzyme immunoassays of eicosanoids using acetylcholine esterase as label: an alternative to radioimmunoassay

P. Pradelles, Jacques Grassi, Jacques Maclouf · Analytical Chemistry · 1985 · 704 citations

Allergy, Biochemistry, Immunotoxicology +12

Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids.

Leslie J. Crofford, R L Wilder, Ari Ristimäki et al. · Journal of Clinical Investigation · 1994 · 659 citations · Full text

Immunology, Pathology, Cox-2 Expression +19

Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment

Colin Funk, Lena B. Funk, Matthew Kennedy et al. · The FASEB Journal · 1991 · 575 citations

Genetics, Cdna Cloning, Blood Cell +20