Revista Brasileira de Parasitologia Veterinária/Brazilian Journal of Veterinary Parasitology · 2010 · 17 citations · 4 references
Veterinary MedicineAnimal SciencesVeterinary ParasitologyGoat MedicineHelminthologyParasitologyAnthelmintic PharmacologyGoat PharmacologyIntestinal ParasitologyNematode BiologyNematode PathogenesisAnthelmintic AgentsAnthelmintic ToxicityGoat Anthelmintic PharmacologyHelminth BiologyIntestinal NematodesLarval Development AssayMechanisms Of Anthelmintic ActionVeterinary Anthelmintics
It was evaluated the anthelmintic activity of Agave sisalana (sisal) juice against gastrointestinal nematodes and its potential toxic effects in goats. In vitro tests showed more than 95% reduction in larval counts of the genus Haemonchus spp. at concentrations between 86.5 and 146.3 mg.mL(-1). In vivo the percent reduction of larvae of the fourth (L4) and fifth (L5) stages of Haemonchus, Oesophagostomum and Trichostrongylus was less than 95% in groups GI and GII, and between 80 and 90% in group GIII. A. sisalana juice at the concentrations tested in vitro was effective against gastrointestinal nematodes in goats; however, its anthelmintic efficacy was reduced when administered to animals.
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