The integrated and free states of Streptomyces griseus plasmid pSG1

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Chromatin, Dna Sequencing, Dna +15

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

H.C. Birnboim, Janine Doly · Nucleic Acids Research · 1979 · 14.8K citations · Full text

Genetics, Bacteriology, Bacteriophage +18

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

Peter Rigby, Marianne Dieckmann, Carl Rhodes et al. · Journal of Molecular Biology · 1977 · 11.7K citations

Nucleic Acid Chemistry, High Specific Activity, Biochemistry +8

A procedure for the isolation of deoxyribonucleic acid from micro-organisms

Julius Marmur · Journal of Molecular Biology · 1961 · 11.6K citations

Biology, Dna Sequencing, Nucleic Acid Chemistry +11

Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. 1977.

Francisco Bolívar, Rodriguez Rl, Greene Pj et al. · PubMed · 1992 · 4.7K citations

Engineering, Genetic Engineering, Vehicle Technology +2