Nkx-2.5 Gene Induction in Mice Is Mediated by a Smad Consensus Regulatory Region

Controlling TGF-beta signaling.

Joan Massagué, Ye-Guang Chen · PubMed · 2000 · 1.8K citations

Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene

Sylviane Dennler · The EMBO Journal · 1998 · 1.8K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +9

Controlling TGF-β signaling

Joan Massagué, Ye‐Guang Chen · Genes & Development · 2000 · 1.6K citations · Full text

Congenital Heart Disease Caused by Mutations in the Transcription Factor <i>NKX2-5</i>

Jean‐Jacques Schott, D. Woodrow Benson, Craig T. Basson et al. · Science · 1998 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +17

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5.

Ian Lyons, Linda M. Parsons, Lynne Hartley et al. · Genes & Development · 1995 · 1.1K citations · Full text

Life Sciences, Developmental Biology, Genetics +15