Concepedia

Induction of apoptosis by cigarette smoke via ROS-dependent endoplasmic reticulum stress and CCAAT/enhancer-binding protein-homologous protein (CHOP)

Yasuhiro Tagawa, Nobuhiko Hiramatsu, Ayumi Kasai, Kunihiro Hayakawa, Maro Okamura, Jian Yao, Masanori Kitamura

Free Radical Biology and Medicine · 2008 · 169 citations · 32 references

Concepts

Life SciencesMolecular BiologyToxicologyApoptosisCell SignalingSignal TransductionApoptosis RegulationApoptotic Signal TransductionApoptotic SignalingBcl-2 Family ProteinsEndoplasmic Reticulum Stress-induced ApoptosisIntrinsic Apoptotic PathwayApoptotic Signaling PathwaysCcaat/enhancer-binding Protein RegulationChop-dependent Cell DeathEndoplasmic Reticulum StressEndoplasmic Reticulum Stress ApoptosisEndoplasmic Reticulum Stress ResponsesEndoplasmic Reticulum Stress-induced Cell Death

References

32

The Pathophysiology of Mitochondrial Cell Death

Douglas R. Green, Guido Kroemer · Science · 2004 · 3.4K citations

Life Sciences, Cell Biology, Molecular Biology +17

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β

Toshiyuki Nakagawa, Hong Zhu, Nobuhiro Morishima et al. · Nature · 2000 · 3.3K citations

Life Sciences, Biochemistry, Cell Biology +12

Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells

Heather P. Harding, Isabel Novoa, Yuhong Zhang et al. · Molecular Cell · 2000 · 3.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

Hélène Zinszner, Masahiko Kuroda, X. Wang et al. · Genes & Development · 1998 · 2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Free-radical chemistry of cigarette smoke and its toxicological implications.

D. F. CHURCH, W. A. PRYOR · Environmental Health Perspectives · 1985 · 1.4K citations · Full text

Life Sciences, Biochemistry, Toxicology +13