Prognostic Factors Predictive of Survival and Local Recurrence for Extremity Soft Tissue Sarcoma

Abstract

The use of mitotic activity along with grade, size, histologic type, and age at diagnosis is prognostic for survival in extremity soft tissue sarcoma. The use of an objective pathologic feature, such as mean mitotic activity, is also useful in selecting patients for future systemic neoadjuvant or adjuvant trials and primary therapy.