The Journal of Antibiotics · 1993 · 39 citations · 5 references
Life SciencesMedicinal ChemistryMicrobiologyMycologyAntifungal AgentsAntifungal ResistanceFungal InfectionsFungal Natural Product BiosynthesisFungal Secondary MetabolitesPlant-pathogenic FungiAntifungal AntibioticsFungal Bioactive CompoundsNatural Antifungal CompoundsNew Antifungal AgentsNovel Antifungal Drug Development
Three macrocyclic polylactones have been isolated from Penicillium verruculosum. Two were found to be novel and the third to be identical with NG-012(1). Their structures were elucidated by spectroscopic and chemical methods. A full assignment of 1H- and 13C-resonances in acetone-d6 are given for all three compounds. The compounds show antifungal activity.
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