Genetic variations of the dihydrofolate reductase gene of Plasmodium vivax in Mandalay Division, Myanmar

Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria.

David S. Peterson, David Walliker, Thomas E. Wellems · Proceedings of the National Academy of Sciences · 1988 · 650 citations · Full text

Point Mutations, Biochemistry, Falciparum Malaria +13

Therapeutic Responses to Different Antimalarial Drugs in Vivax Malaria

Sasithon Pukrittayakamee, Arun Chantra, J. A. Simpson et al. · Antimicrobial Agents and Chemotherapy · 2000 · 175 citations · Full text

Hospital Cost Containment in the 1980s

William B. Schwartz, Daniel N. Mendelson · New England Journal of Medicine · 1991 · 162 citations

Association of Genetic Mutations in <i>Plasmodium vivax dhfr</i> with Resistance to Sulfadoxine-Pyrimethamine: Geographical and Clinical Correlates

Mallika Imwong, Sasithon Pukrittakayamee, Sornchai Looareesuwan et al. · Antimicrobial Agents and Chemotherapy · 2001 · 151 citations · Full text

Novel Point Mutations in the Dihydrofolate Reductase Gene of <i>Plasmodium vivax</i> : Evidence for Sequential Selection by Drug Pressure

Mallika Imwong, Sasithon Pukrittayakamee, Laurent Rénia et al. · Antimicrobial Agents and Chemotherapy · 2003 · 148 citations · Full text