Pediatric Dermatology · 1987 · 17 citations · 4 references
MedicineDermatologyPathologyDermatopathologyHistopathologyPediatric DermatologyImmunopathology Of SkinInflammatory Skin DisordersPediatric DermatopathologyBullous DermatosesBullous Lichen PlanusDapsone TherapyHistologic ExaminationHistopathology Of Skin LesionsImmunofluorescence FindingsIndirect Immunofluorescence AssayLichenoid Dermatitis
A child with previous lichenoid lesions had bullae refractory to antistaphylococcal antibiotics. Biopsy of a bulla showed histologic changes of bullous lichen planus. Indirect immunofluorescence using the patient's serum on a perilesional bulla biopsy showed positive staining for IgA and IgG in the stratum granulosum and stratum corneum, confirming the diagnosis. The lesions resolved with dapsone treatment.
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