Processed N-termini of mature proteins in higher eukaryotes and their major contribution to dynamic proteomics

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

Henrik Nielsen, Jacob Engelbrecht, Søren Brunak et al. · Protein Engineering Design and Selection · 1997 · 5.4K citations · Full text

Cleavage Sites, Signal Recognition, Molecular Biology +23

Predicting Subcellular Localization of Proteins Based on their N-terminal Amino Acid Sequence

Olof Emanuelsson, Henrik Nielsen, Søren Brunak et al. · Journal of Molecular Biology · 2000 · 4.3K citations

Biochemistry, Biomolecular Structure Prediction, Protein Folding +13

Cyclin is degraded by the ubiquitin pathway

Michael Glotzer, Andrew W. Murray, Marc W. Kirschner · Nature · 1991 · 2.4K citations

Protein Function, Protein Degradation, Ubiquitin Pathway +4

Patterns of Amino Acids near Signal‐Sequence Cleavage Sites

Gunnar von Heijne · European Journal of Biochemistry · 1983 · 2.3K citations · Full text

In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue

Andreas Bachmair, Daniel Finley, Alexander Varshavsky · Science · 1986 · 2K citations