Enantioretentive alkylation of acyclic amino acids

Alkylation of amino acids without loss of the optical activity: preparation of .alpha.-substituted proline derivatives. A case of self-reproduction of chirality

Dieter Seebàch, M. BOES, Reto Naef et al. · Journal of the American Chemical Society · 1983 · 390 citations

Natural Sciences, Biochemistry, Chemistry +15

Synthesis of 9-fluorenylmethyloxycarbonyl-protected N-alkyl amino acids by reduction of oxazolidinones

Roger Freidinger, Jeffery S. Hinkle, Debra S. Perlow · The Journal of Organic Chemistry · 1983 · 174 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Enantioselective Generation and Diastereoselective Reactions of Chiral Enolates Derived from α‐Heterosubstituted Carboxylic Acids. Preliminary Communication

Dieter Seebàch, Reto Naef · Helvetica Chimica Acta · 1981 · 161 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

Synthesis of enantiomerically enriched atrolactic acid and other α-hydroxy acids

Gy. Fráter, Urs Müller, Wulf Günther · Tetrahedron Letters · 1981 · 81 citations

Natural Sciences, Chemistry, Organic Chemistry +5

Asymmetric Syntheses via Heterocyclic Intermediates; XII¹. Enantioselective Synthesis of (<i>R</i>)-α-Amino Acids using tert-Leucine as Chiral Auxiliary Reagent

Ulrich Schöllkopf, Hans‐Jürgen Neubauer · Synthesis · 1982 · 62 citations

Natural Sciences, Chemistry, Organic Chemistry +12