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Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N′-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII

Molecular PharmacologyMedicinal ChemistryBiochemistryMedicineNatural SciencesHuman Cytosolic IsozymesAnti-cancer AgentDrug DevelopmentChemical BiologyPharmacologyPharmaceutical ChemistryInhibitory ActivityDrug DiscoveryCarbonic Anhydrase Inhibitors