Linear Loss of Insulin Secretory Capacity During the Last Six Months Preceding IDDM: No effect of antiedematous therapy with ketotifen - Concepedia

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Linear Loss of Insulin Secretory Capacity During the Last Six Months Preceding IDDM: No effect of antiedematous therapy with ketotifen

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References

1994

Year

K. Böhmer, Hubert Kolb, B. Kuglin, Jürgen Zielasek, A Hübinger, E. F. Lampeter, Bruno Weber, Victoria Kolb-Bachofen, H.-U. Jastram, Jörg Bertrams,

Abstract

The study could not demonstrate preservation of beta-cell function by ketotifen in the late stage before manifestation of clinical diabetes. Manifestation is preceded in the last 6 months by a steady loss of the FPIR without rapid deterioration immediately before diagnosis and without signs of increased immune activity.