The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone

Abstract

Nonstandard abbreviations used: calcium-sensing receptor (CaR); extracellular calcium (Ca 2+ o); parathyroid hormone (PTH); familial hypocalciuric hypercalcemia (FHH); neonatal severe hyperparathyroidism (NSHPT); fractional excretion of calcium (FECa); calcium transporter type 1 (CaT1); calcium transporter type 2 (CaT2/ECaC); bone mineral density (BMD); tartrateresistant acid phosphatase (TRAP); mineral apposition rate (MAR); bone formation rate (BFR).