In Situ Expression of <i>cagA</i> and Risk of Gastroduodenal Disease in <i>Helicobacter pylori</i>–infected Children

Abstract

Thus, cagA in situ expression is increased in H pylori-infected children with peptic ulcers and may play a role in the pathogenesis of peptic ulcer disease during childhood. Determination of in situ expression of cagA complements traditional isolation and in vitro testing of single-colony isolates.