EVIDENCE OF ADENOSINE 5′-TRIPHOSPHATE RELEASE FROM NERVE AND P2X-PURINOCEPTOR MEDIATED CONTRACTION DURING ELECTRICAL STIMULATION OF RAT URINARY BLADDER SMOOTH MUSCLE

Abstract

The results of the present study give evidence to support purinergic nerve-mediated bladder smooth muscle contractions in the rat. Among the purine nucleotides, ATP is the dominant purinergic neurotransmitter released and P2x receptor activation is responsible for the NANC contractile response.